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Valsartan

Release date:2013-06-20 Browsing times:


CAS NO.                                        137862-53-4
English name                                   Valsartan
Chemical name      N-(1- valeryl)-N-[4-[2-(1H- tetrazole -5- pyridyl) phenyl] phenmethyl]-L- Valine
Chemical Classification                    pharmaceutical intermediates
Chemical formula                               C24H29N5O3
Specification                                  USP30
Storage Condition                      cool,dry, room-temperature and well-closed container
Guaranteed Analysis 
Appearance                             white or almost white crystalline powder
Identify                               IR must conform to reference standard
                                 HPLC must conform to reference standard
Absorbance                                      ≤0.02
Moisture                                        ≤2.0%
Residue on ignition                             ≤0.1%
Heavy Metals                                    ≤0.001%
Relate Compounds   
Compound A                               ≤0.1%
Compound B                               ≤0.2%
Compound C                               ≤0.1%
 Any other individual impurity             ≤0.10%
 Total impurity (excluding R-isomer)       ≤0.3%
Residual solvents  
Ethyl acetate                                ≤0.5%
Dichloromethane                            ≤0.06%
Methanol                                    ≤0.3%
N,N-Dimethylformamide:                     ≤0.088%
Assay (HPLC)                                     98.0~102.0%
physical characteristics
White or almost white crystalline powder, odorless, slightly moist.  easily dissolved in methanol and ethanol , 
sparingly soluble in ethyl acetate, slightly soluble in dichloromethane, almost insoluble in water.
usage
Valsartan is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of
hypertension patients who used other antihypertensive drugs without efficacy , is a new generation of highly 
efficient antihypertensive drugs.
package
In 25kg per fiber drum inner polythene bags。

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